Detection of helicobacter pylori in pediatric patients with adenotonsillar hypertrophy

Background: Adenotonsillar hypertrophy is one of the most prevalent causes of upper airway obstruction in pediatric patients. Recent studies have shown contradictory findings about helicobacter pylori colonization in adenotonsilar tissue and its role on adenotonsilar hypertrophy. According to this, we decided to investigate relationship between helicobacter pylori colonization and adenotonsillar hypertrophy. Methods: This is a comparative study in otorhinolaryngology department of Amir Almoemenin hospital in Semnan. In this study, pediatric patients with adenotosillar hypertrophy (n=50) were compared with control group (n=50) in terms of H. pylori colonization in adenotonsillar tissue. All of them were examined by urease breath test (UBT). Adenoid and tonsil biopsy specimens (in 30 patients with adenotonsilectomy) were collected and underwent the RUT for investigating colonization of Helicobacter pylori. Results: Fourteen percent of patients with adenotonsillar hypertrophy and 20% of control were found helicobacter pylori infection. There was no significant association between helicobacter pylori and adenotonsillar hypertrophy (odds ratio: 0.65 with confidence interval: 0.2-2.09). Conclusion: This study showed lack of relationship between adenotonsillar hypertrophy and Helicobacter pylori. However, more studies and samples are needed to provide a definitive judgment.