Title of article
Effect of Maternal Body Mass Index on the Efficacy of Antenatal Betamethasone Administration in Neonatal Outcomes
Author/Authors
Mirzamoradi ، Masoumeh Mahdieh Hospital - Shahid Beheshti University of Medical Sciences , Saleh Gargari ، Soraya Infertility and Reproductive Health Research Center - Shahid Beheshti University of Medical Sciences , Pooransari ، Parichehr Shohada Hospital - Shahid Beheshti University of Medical Sciences , Shirazi ، Mahboobeh Department of Perinatology - Yas Hospital Complex, Maternal, Fetal, and Neonatal Research Center, Family Health Institute - Tehran University of Medical Sciences , Ahmadyan ، Maryam Mahdieh Hospital - Shahid Beheshti University of Medical Sciences , Naeiji ، Zahra Department of Gynecology and Obstetrics - Mahdieh Hospital - Shahid Beheshti University of Medical Sciences , Rahmati ، Nayereh Department of Obstetrics and Gynecology - Mahdieh Hospital - Shahid Beheshti University of Medical Sciences , Arbabzadeh ، Taraneh Shohada Hospital - Shahid Beheshti University of Medical Sciences , Ahmadyan ، Neda Breastfeeding Research Center, Family Health Institute - Tehran University of Medical Sciences
From page
21
To page
28
Abstract
Background: Maternal obesity affects the health of infants and pregnancy outcomes. Few studies, to the best of our knowledge, have assessed the relationship between maternal body mass index (BMI) at antenatal corticosteroid therapy (ACS) and the frequency of preterm adverse outcomes results of which were discrepant. The present study aimed to investigate the prevalence of several neonatal morbidities based on maternal BMI among pregnant women who received a single course of ACS. Methods: The present retrospective study was conducted on pregnant women referred to Mahdieh Hospital in Tehran, Iran between 2021 and 2022. Medical records of pregnant women were included who received a single course of betamethasone with the risk of preterm birth. The mothers were divided into three groups in terms of weight after checking the inclusion criteria. Clinical characteristics and neonatal outcomes were collected and analyzed using soft statistics. Results: A total of 610 medical records (30.49%: normal weight, 57.54%: overweight, and 11.98%: obese) were included. Also, the cesarean section rate in overweight and obese cases was significantly higher than that of the normal BMI group (P 0.05). No significant relationship was observed between maternal BMI and neonatal mortality or morbidity (P 0.05). Conclusion: BMI was more associated with increased cesarean section rate in overweight and obese groups. However, no significant relationship was observed between maternal BMI and neonatal outcomes. This result suggests that BMI fails to affect the efficacy of betamethasone
Keywords
Betamethasone , Body mass index , Perinatal , Premature birth , Neonatal
Journal title
Iranian Journal of Neonatology (IJN)
Journal title
Iranian Journal of Neonatology (IJN)
Record number
2729567
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