Title of article
Peptide Nucleic Acid for Rapid Gap-selective Hydrolysis of DNA by Ce(IV)/EDTA Complex
Author/Authors
Komiyama، Makoto نويسنده , , Yamamoto، Yoji نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
-75
From page
76
To page
0
Abstract
When gap-structures are formed in substrate DNA by using peptide nucleic acid (PNA), these sites are rapidly and selectively hydrolyzed by Ce(IV)/EDTA complex. Scission efficiency at the gap-site is 6-fold higher than that obtained by use of the corresponding DNA additives. Site-selectivity is also higher. The DNA/PNA duplexes must take anti-parallel direction here.
Keywords
Genetic-fuzzy system , Surface finish , Power requirement , grinding , Application-production research , prediction
Journal title
CHEMISTRY LETTERS
Serial Year
2004
Journal title
CHEMISTRY LETTERS
Record number
27348
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