One-Pot synthesis of oxindoles derivatives as effective antimicrobial agents by Nano-Magnesium aluminate as an effective aatalyst

A magnesium aluminate catalyzed environmentally benign strategy for the synthesis of oxindole derivatives via the one-pot reaction between indole and isatin is established under reflux conditions in excellent yields. The reaction was carried out in ethanol and in the catalyst presence to give the corresponding oxindoles derivatives in high yields. The low cost, availability of catalyst, and the novel and green procedure makes this strategy more useful for the preparation of xanthene derivatives.