Title of article
Effect of ascorbic acid treatment with angiogenesis
Author/Authors
Bakhshandeh Bavarsad ، Sareh Department of public management - Faculty of management - University of Shahrekord , Mohammadi ، Amir Department of Immunology - Asthma and Allergy Research Institute, Children s Medical Center - Tehran University of Medical Sciences , Shojaei ، Najme Personalized Medicine Research Center of AmitisGen
From page
17
To page
19
Abstract
Vitamin C plays is a cofactor for enzymes involved in many processes and has effects that are important for cancer transformation, such as antioxidant defense, transcription, and epigenetic regulation of gene expression.Angiogenesis is a normal process required for normal tissue repair and growth. Pathological angiogenesis is characterized by the persistent proliferation of endothelial cells and formation of blood vessels.The current study evaluated the effect of ascorbic acid on angiogenesis by investigating the expression of genes related to angiogenesis after treatment with different doses of ascorbic acid. By changing the concentration and administration time of ascorbic acid, a positive effect on the growth and metastasis of cancer cells in the group injected with ascorbic acid prior to having cancer cells injected into the abdominal cavity .
Keywords
Vitamin C , Angiogenesis , carcinostatic , Breast cancer
Journal title
Personalized Medicine Journal
Journal title
Personalized Medicine Journal
Record number
2743043
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