Title of article
Highly Stereoselective Aldol-type Reaction of 2-Bromo-2,3,3,3-tetrafluoropropanamide with Aldehydes Leading to erythro-(alpha)-Fluoro-(alpha)-(trifluoromethyl)-(beta)-hydroxy Amides
Author/Authors
Konno، Tsutomu نويسنده , , Ishihara، Takashi نويسنده , , Yamanaka، Hiroki نويسنده , , Sato، Kei نويسنده , , Sekiguchi، Takashi نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
-153
From page
154
To page
0
Abstract
N-Methoxy-N-methyl-2-bromo-2,3,3,3-tetrafluoropropanamide underwent highly stereoselective aldol-type reaction with various aldehydes under the influence of triphenylphosphine—a catalytic amount of titanium(IV) isopropoxide at room temperature to give the erythro-isomers of (alpha)-fluoro-(alpha)-(trifluoromethyl)-(beta)-hydroxy amides preferentially in good to excellent yields.
Keywords
Genetic-fuzzy system , prediction , Surface finish , grinding , Power requirement , Application-production research
Journal title
CHEMISTRY LETTERS
Serial Year
2004
Journal title
CHEMISTRY LETTERS
Record number
27462
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