The Combination of Remifentanil + Dexamethasone Has Favorable Effects in Management of Pain after Cesarean Section: A Systematic Review

Introduction: Concerning the use of remifentanil and dexamethasone drugs each alone in creating painless childbirth, and also in the process of facilitating childbirth to increase the pain as much as possible and minimize the complications and possibly help the progress of labor, we decided that the effect of dexamethasone in combination to investigate with remifentanil in the control of labor pain in this systematic review. Methodology: In this review article, the keywords that were selected based on MeSh and searched based on them included Remifentanil, labor, pain, Dexamethasone, combination, acceptability, effectiveness, vaginal delivery, VAS, headache, surgical delivery, hemodynamically stable, and hemodynamically. Results: The average pain intensity in the treatment groups was measured and evaluated on four occasions 30, 60, 120, and 180 minutes after the intervention. The results showed that the average numerical scale of pain intensity measurement based on VAS in the group receiving remifentanil and dexamethasone 30 minutes after the start of the intervention was equal to 6.06 and the average of the same scores in the group receiving remifentanil at the same time was 6.83. Conclusion: The simultaneous use of remifentanil and dexamethasone is recommended in comparison to the use of remifentanil because it is safe for both mother and child and causes more favorable analgesia and fewer complications during childbirth.