Title of article
Evaluation of Potential Effect of Bone Marrow Mast Cells on Burn Wound Healing in Rat
Author/Authors
Mousazadeh ، Shima Department of Pathology - Faculty of Veterinary Medicine - Islamic Azad University, Urmia Branch , Amniattalab ، Amir Department of Pathology - Faculty of Veterinary Medicine - Islamic Azad University, Urmia Branch , Mohammadi ، Rahim Department of Surgery and Diagnostic Imaging - Faculty of Veterinary Medicine - Urmia University
From page
82
To page
88
Abstract
The objective of this work was to assess the potential effect of bone marrow mast cells (BMMCs) on burn wound healing in rats. We included 45 male rats into three groups of 15 animals each: CNTRL group: We treated the burn wounds with normal saline (0.1 ml). TRTMENT group: In this group, the burn wounds were treated with bone marrow mast cells (1× 106/ml). SSD (Positive control) group: In this group, the wounds were treated with silver sulfadiazine 1% ointment. Wound area reduction measurements, histopathological studies, and biochemical assessments levels showed significant differences between rats in TRTMENT group in comparison with other groups (p 0.05). Accelerated repair of the wounds in TRTMENT group showed that local application of BMMCs could be taken into consideration in burn wound healing.
Keywords
Burn wound , BMMCs , Rat
Journal title
Iranian Journal of Veterinary Surgery (IJVS)
Journal title
Iranian Journal of Veterinary Surgery (IJVS)
Record number
2760774
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