Towards Efficient Catalysts via Biomimetic Chemistry for Diphenols and Aminophenols Aerobic Oxidation

Biomimetic chemistry is a new environment-friendly approach that is inspired by biological processes, to produce new catalysts, and to develop ‘green’ synthetic routes to chemical catalysts based on the benefits of biological systems, aimed to find sustainable solutions to environmental and economic problems. In this paper, we will begin with overviews of two metalloproteins containing copper, which are catechol oxidase and phenoxazinone synthase; this is followed by analysis, and interpretation of some published results in the literature, concerning several attempts to elaborate new catalysts via biomimetic approach for diphenols and aminophenols aerobic oxidation. In order to save the cost of product development, increase efficiency, and eliminate waste; we have presented a theoretical study named Quantitative Structure–Activity Relationship (QSAR) to predict the catalytic activity and physicochemical properties by rational means, with the aim of contributing to the development of the biomimetic approach, and to increase the efficiency of catalysts, by not following leads that are unlikely to be successful.