Epidemiology and clinical characteristics of Chandipura virus

Chandipura virus is an emerging arbovirus that poses significant public health challenges, especially in South Asia. Chandipura virus infection is one of the neglected diseases that is receiving limited attention. This virus primarily affects young children and has been associated with outbreaks of influenza-like illness and acute encephalitis, leading to high morbidity and mortality rates with death occurring within 48-72 h of the onset of symptoms in most of the affected populations. The outbreaks occur majorly during near-monsoon season especially in regions with favorable ecological conditions for sand fly proliferation. Currently, no vaccines or therapeutics are available, depicting the ongoing public health challenge posed by this emerging infectious virus. This review provides an overview of epidemiology, clinical features, and public health implications of Chandipura virus infections. Understanding the epidemiological patterns, clinical manifestations, and public health responses to the Chandipura virus is essential for developing effective preventive strategies and enhancing patient outcomes.