Green Synthesis, Characterization, and Biological Activity of Aryl Azo Schiff Bases

This study reflected novel and eco-friendly methods approving the green synthesis of various Schiff’s bases by sonication, microwave irradiation, stirring, and grinding methods using DHE and various aromatic aldehydes. We also offered the synthesis of aryl azo Schiff base in different ways and compared the way of synthesizing it. As a result, sonication and microwave irradiation proved the modest technique to synthesize aryl azo Schiff base. This technique is experimentally green, simple, of greater yielding, clean, and with compact reaction times. Also, the synthesized compounds were tested for their antibacterial activity. The most admirable results were observed and it could be a potential starting point to develop innovative lead compounds fight against a panel of some human disease-causing pathogens bacteria.