Title of article
Functional Regulation of Myoglobin by Iron Corrphycene
Author/Authors
Neya، Saburo نويسنده , , Funasaki، Noriaki نويسنده , , Hori، Hiroshi نويسنده , , Imai، Kiyohiro نويسنده , , Nagatomo، Shigenori نويسنده , , Iwase، Tadashi نويسنده , , Yonetani، Takashi نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
-988
From page
989
To page
0
Abstract
Iron corrphycene, a novel isomeric heme, was incorporated into myoglobin to examine the influence of heme deformation on the function. The reconstituted protein, although functionally active, exhibits extremely lower affinities for O2 and CO as compared with the native protein. The functional anomaly was explained in terms of modified iron reactivity in the trapezoidal coordination core.
Keywords
Goodness of fit , Model diagnosis , Parametric bootstrap , Restricted latent class models , Identifiability
Journal title
CHEMISTRY LETTERS
Serial Year
1999
Journal title
CHEMISTRY LETTERS
Record number
27848
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