Title of article
A Cation-exchange Resin Promoted Imino Aldol Reaction, Leading to the Synthesis of 2-Isocephem and 2-Oxa-isocephem
Author/Authors
Hachiya، Iwao نويسنده , , Shimizu، Makoto نويسنده , , Tachi، Masanori نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
-1393
From page
1394
To page
0
Abstract
Imino aldol reaction of ketene silyl acetals with the chiral imine 1 proceeds smoothly to give(beta)-amino esters in good yields with high diasetereoselectivity under the influence of a cation-exchange resin, and the subsequent functional group transformations provide a formal synthesis of 2-isocephem and 2-oxa-isocephem (beta)-lactam antibiotics.
Keywords
grinding , Genetic-fuzzy system , Application-production research , prediction , Surface finish , Power requirement
Journal title
CHEMISTRY LETTERS
Serial Year
2004
Journal title
CHEMISTRY LETTERS
Record number
28854
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