Title of article
Growth hormone receptor antagonists therapy for acromegaly
Author/Authors
Craig Parkinson، نويسنده , , Peter J. Trainer، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
12
From page
419
To page
430
Abstract
Knowledge of the interaction between growth hormone (GH) and the growth hormone receptor (GHR) has led to the rational design of a GHR antagonist. An analogue of GH able to block the action of GH at the cellular level offers greater specificity of effect compared with current medical therapies and is not dependent on tumour characteristics. This chapter reviews the interaction between GH and the GHR, and discusses the outstanding issues regarding GHR antagonist therapy in acromegaly.
Keywords
Treatment , Growth hormone , Acromegaly , growth hormone receptor antagonist.
Journal title
Best Practice and Research Clinical Endocrinology and Metabolism
Serial Year
1999
Journal title
Best Practice and Research Clinical Endocrinology and Metabolism
Record number
465750
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