Allogeneic haemopoietic stem cell transplantation for non-Hodgkinʹs lymphoma

This chapter outlines the rationale for allogeneic haemopoietic stem cell transplantation in non-Hodgkinʹs lymphoma and pertinent results from published studies. Trials comparing allogeneic with autologous transplantation are discussed, as are disease-specific results for low-grade (including transformed), mantle cell and high-grade (Burkittʹs and lymphoblastic) subtypes of the disease. Allogeneic transplantation for non-Hodgkinʹs lymphoma in the paediatric population, the use of unrelated donors, allografting after failed autologous or allogeneic transplantation, the graft-versus-lymphoma effect, the use of donor leukocyte infusions and non-myeloablative allografts are considered.