Title of article
Stimulation of anti-melanoma immune effectors via modified tumour cells exhibiting inhibited IGF-I and low CD9
Author/Authors
Severine Trabado، نويسنده , , Pascale Nguyen Van Binh، نويسنده , , Chantal Martin، نويسنده , , Christiane Lafarge-Frayssinet، نويسنده , , Yu-Chun Lone، نويسنده , , Jerzy Trojan، نويسنده , , Jean-Michel Warnet، نويسنده , , Huynh Thien Duc، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
494
To page
498
Abstract
Modified melanoma cells (B16-F0.MOD) characterized by inhibited IGF-I, CD9 low but not their wild-type counterparts (B16-F0.WT), IGF-I positive, CD9 high, were shown to be immunogenic for syngeneic hosts. C57BL/6 syngeneic recipients vaccinated with B16-F0.MOD cells developed immune effectors that were observed at the humoral as well as cellular levels. These immune effectors were shown to be capable of controlling in vitro tumour growth and in vivo tumour progression.
Keywords
Modified melanoma cells , Cellular/humoral immune effectors
Journal title
Biomedicine and Pharmacotherapy
Serial Year
2007
Journal title
Biomedicine and Pharmacotherapy
Record number
477995
Link To Document