Title of article
Influence of anticoagulants on the measurement of S100B protein in blood
Author/Authors
Adriano B. L. Tort، نويسنده , , Marcelo O. Dietrich، نويسنده , , Carlos A. Gonçalves، نويسنده , , Diogo O. Souza، نويسنده , , Luis V. C. Portela، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
629
To page
632
Abstract
Objective
Evaluate anticoagulants influence on blood S100B levels.
Design and methods
Blood from 18 healthy adult subjects were collected using: no anticoagulants; EDTA; heparin; and citrate. S100B levels were determined using LIA-mat assay.
Results
Heparin and citrate increased S100B levels (p< 0.001), whereas EDTA had no effect (p = 0.24). Heparin samples were highly (r2 = 0.97, p< 0.001), citrate samples were moderately (r2 = 0.49, p< 0.001), and EDTA samples were not (r2 = 0.22, p = 0.059) correlated with serum samples.
Conclusion
When anticoagulant is required, heparin should be the primary choice
Keywords
blood , Anticoagulants , S100B , Immunoluminometric assay
Journal title
Clinical Biochemistry
Serial Year
2003
Journal title
Clinical Biochemistry
Record number
482461
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