Title of article
Metabolic consideration of epiphyseal growth: Survival responses in a taxing environment
Author/Authors
Irving M. Shapiro، نويسنده , , Vickram Srinivas، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
7
From page
561
To page
567
Abstract
The goal of this review is to examine some of the metabolic features of the maturing chondrocyte within the epiphyseal growth plate. The energy status of the tissue is examined in light of the energy needs of the tissue and the availability of oxygen. The role of HIF, PHDs and other proteins concerned with transduction of the oxemic response is considered and related to chondrocyte survival in a complex extracellular matrix.
Keywords
chondrocyte , Epiphyseal growth plate , PHD , Oxygen , HIF , mTOR , Akt , AMPK , metabolism
Journal title
Bone
Serial Year
2007
Journal title
Bone
Record number
496161
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