Title of article
Hypermutation in antibody affinity maturation
Author/Authors
Matthias Wabl، نويسنده , , Marilia Cascalho، نويسنده , , Charles Steinberg، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
186
To page
189
Abstract
By studying the role of mismatch repair in hypermutation at the immunoglobulin loci, the field of antibody hypermutation has been integrated into the larger area of DNA repair. Trans-acting factors — Ku70, Ku80 and possibly SWAP-70 — have been identified for the temporally related but not mechanistically related immunoglobulin heavy-chain class-switch.
Journal title
Current Opinion in Immunology
Serial Year
1999
Journal title
Current Opinion in Immunology
Record number
511827
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