Title of article
The role of IL-18 in innate immunity
Author/Authors
Shizuo Akira، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
5
From page
59
To page
63
Abstract
IL-18 — a novel cytokine with potent IFN-γ-inducing activities — plays an important role in the Th1-mediated immune response in collaboration with IL-12. IL-18 is a member of the IL-1 family. The IL-18 receptor system and its signal transduction pathway are analogous to those of the IL-1 receptor. Mice deficient in IL-18 have demonstrated its critical role in natural killer cell activity and in vivo Th1 response.
Journal title
Current Opinion in Immunology
Serial Year
2000
Journal title
Current Opinion in Immunology
Record number
511918
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