Title of article
Synthesis of [11C]methyl ketones via [11C]methylation of dithiane intermediates
Author/Authors
P. H. Elsinga، نويسنده , , E. Fluks، نويسنده , , E. J. F. Franssen، نويسنده , , G. M. Visser، نويسنده , , W. Vaalburg، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
3
From page
57
To page
59
Abstract
A versatile synthetic route to obtain [11C]methyl ketones from aldehydes is described. Test reactions with [11C]CH3I on the model compounds 2-methyl- and 2-cyclohexyl- 1,3-dithiane followed by oxidation with N-bromosuccinimide gave almost quantitative radiochemical yields. Reaction of [11C]CH3I with 2-phenylethyl-1,3-dithiane yielded the corresponding [11C]methyl ketone in 80% radiochemical yield together with an unidentified side-product on oxidation with N-bromosuccinimide.
Journal title
Applied Radiation and Isotopes
Serial Year
1996
Journal title
Applied Radiation and Isotopes
Record number
539432
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