A review of radiologically important trace elements in human bones

The authors recently compiled and reviewed the literature for minor and trace elements in human bones and teeth as a part of an International Atomic Energy Agency (IAEA) study. Various aspects of elemental composition, analytical methodologies, quality assurance and quality control methods for hard tissue analysis were evaluated. Important data on selected radiologically important elements (Cs, Pu, Ra, Sr, Th and U) in calcified tissue from various countries are discussed. The results of this compilation study suggest a need for new reference materials with matrix properties similar to bones including one with separated cortical and trabecular segments.