Title of article
Tritium labelling and characterization of the cognition enhancing drug tacrine using several precursors
Author/Authors
Judith A. Egan، نويسنده , , Richard P. Nugent، نويسنده , , Crist N. Filer، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
837
To page
840
Abstract
Tacrine and its analogues have shown promise as cognition enhancers and potential chemotherapeutic agents for Alzheimerʹs disease. [3H]tacrine was required to explore its mechanism of action via receptor binding assay and the radioligand was prepared by means of catalytic dehalogenation of several brominated precursors.
Keywords
Tritium , Tacrine , Tritium NMR
Journal title
Applied Radiation and Isotopes
Serial Year
2002
Journal title
Applied Radiation and Isotopes
Record number
541374
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