Title of article
Tritium labelling and characterization of the potent imidazoline I1 receptor antagonist [5,7-3H] (±)-efaroxan at high specific activity
Author/Authors
Judith A. Egan، نويسنده , , Crist N. Filer، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
3
From page
675
To page
677
Abstract
(±)-Efaroxan 1 is a selective antagonist at the imidazoline I1 receptor. [3H] (±)-Efaroxan was required to explore its mechanism of action via receptor binding assay, and the radioligand was prepared by means of catalytic dehalogenation of a dibrominated precursor with tritium.
Keywords
Tritium , Tritium NMR , (7)-Efaroxan
Journal title
Applied Radiation and Isotopes
Serial Year
2003
Journal title
Applied Radiation and Isotopes
Record number
541482
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