Title of article
55Cobalt complexes with pendant carbohydrates as potential PET imaging agents
Author/Authors
Cara L. Ferreira، نويسنده , , Suzanne Lapi، نويسنده , , Jennifer Steele، نويسنده , , David E. Green II، نويسنده , , Thomas J. Ruth، نويسنده , , Michael J. Adam، نويسنده , , Chris Orvig، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
6
From page
1303
To page
1308
Abstract
Bis-ligand cobalt(II) complexes of four 3-hydroxy-4-pyridinone ligands with pendant carbohydrates were synthesized and examined for their potential as radiopharmaceuticals. Non-radioactive complexes were prepared on the macroscopic scale and characterized by elemental analysis, mass spectrometry, IR and UV/visible spectroscopy. Facile radiolabeling produced the 55Co complexes in high radiochemical yields (>95%). Identification of the radiolabeled compounds was accomplished by HPLC comparison with the corresponding non-radioactive complexes.
Keywords
Carbohydrates , Cobalt , 55Co , PET
Journal title
Applied Radiation and Isotopes
Serial Year
2007
Journal title
Applied Radiation and Isotopes
Record number
548318
Link To Document