• Title of article

    Cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphism confers susceptibility to thyroid associated orbitopathy Original Research Article

  • Author/Authors

    Bijayeswar Vaidya، نويسنده , , Helen Imrie، نويسنده , , Petros Perros، نويسنده , , Jane Dickinson، نويسنده , , Mark I. McCarthy، نويسنده , , Pat Kendall-Taylor، نويسنده , , Simon HS Pearce، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    2
  • From page
    743
  • To page
    744
  • Abstract
    Smoking and demographic variables are known to be risk factors for the development of thyroid-associated orbitopathy (TAO) among patients with Gravesʹ hyperthyroidism, but a firm genetic basis for TAO has not been established. We show that the presence and severity of TAO are associated with an allele of the cytotoxic T lymphocyte antigen-4-gene.
  • Journal title
    The Lancet
  • Serial Year
    1999
  • Journal title
    The Lancet
  • Record number

    549366