Title of article
Neonatal end-stage renal failure associated with maternal ingestion of cyclo-oxygenase-type-1 selective inhibitor nimesulide as tocolytic Original Research Article
Author/Authors
Licia Peruzzi، نويسنده , , Bruno Gianoglio، نويسنده , , Maria Gabriella Porcellini، نويسنده , , Rosanna Coppo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
1
From page
1615
To page
1615
Abstract
Cyclo-oxygenase-type-2 (COX-2) enzyme is fundamental for nephrogenesis, upregulated on fetal membranes and myometrium at parturition. Fetal COX-2 inhibition, due to maternal nimesulide assumption, can be responsible for neonatal chronic renal failure.
Journal title
The Lancet
Serial Year
1999
Journal title
The Lancet
Record number
550087
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