Title of article
Immune repopulation after HAART in previously untreated HIV-1-infected children Original Research Article
Author/Authors
DM Gibb، نويسنده , , A Newberry، نويسنده , , N Klein، نويسنده , , A de Rossi، نويسنده , , I Grosch-Woerner، نويسنده , , A Babiker، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
2
From page
1331
To page
1332
Abstract
In 25 vertically HIV-1-infected children receiving highly-active antiretroviral therapy, a 3-log10 reduction in plasma HIV RNA load was maintained for 1 year and was associated with a doubling of the CD4-cell percentage. Most (75%) new CD4 cells carried the CD45RA marker of naive cells and there was only a small rise in memory cells (CD45RO). This pattern of immune restoration differs from adults, and may be due to the presence of a functioning thymus in children.
Journal title
The Lancet
Serial Year
2000
Journal title
The Lancet
Record number
551584
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