Title of article
Lithium-induced increase in human brain grey matter
Author/Authors
Gregory J Moore، نويسنده , , Joseph M. Bebchuk، نويسنده , , Ian B. Wilds، نويسنده , , Guang Chen، نويسنده , , Husseini K Menji، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
2
From page
1241
To page
1242
Abstract
Rodent studies have shown that lithium exerts neurotrophic or neuroprotective effects. We used three-dimensional magnetic resonance imaging and brain segmentation to study pharmacologically-induced increases in grey matter volume with chronic lithium use in patients with bipolar mood disorder. Grey-matter volume increased after 4 weeks of treatment. The increases in grey matter probably occurred because of neurotrophic effects.
Journal title
The Lancet
Serial Year
2000
Journal title
The Lancet
Record number
553238
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