Title of article
Weight gain in infancy and cancer of the ovary
Author/Authors
D. J. P. Barker، نويسنده , , P. D. Winter، نويسنده , , C. Osmond، نويسنده , , D. I. W. Phillips، نويسنده , , H. Y. Sultan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
2
From page
1087
To page
1088
Abstract
The geographic association between ovarian cancer and tall stature suggests a link with rapid growth in early childhood. Among 5585 women born in Hertfordshire, UK, 41 who died from ovarian cancer had had a high rate of weight gain in infancy. Whereas their mean birthweight was the same as that of the other women, their mean weight at 1 year was higher (22·3 pounds [10·1 kg] vs 21·4 pounds [9·7 kg], P=0·01). These observations are consistent with the hypothesis that ovarian cancer is linked to altered patterns of gonadotropin release established in utero when the fetal hypothalamus is imprinted.
Journal title
The Lancet
Serial Year
1995
Journal title
The Lancet
Record number
561908
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