Title of article
cDNA cloning and expression of human lactosylceramide synthase
Author/Authors
Minoru Takizawa، نويسنده , , Tomoko Nomura، نويسنده , , Etsuji Wakisaka، نويسنده , , Naonobu Yoshizuka، نويسنده , , Junken Aoki، نويسنده , , Hiroyuki Arai، نويسنده , , Keizo Inoue، نويسنده , , Michihiro Hattori، نويسنده , , Noboru Matsuo، نويسنده ,
Pages
4
From page
301
To page
304
Abstract
Lactosylceramide synthase is an enzyme that catalyzes the transfer of galactose from UDP-Gal to glucosylceramide, and thus participates in the biosynthesis of most glycolipids in mammals. We have isolated and sequenced the cDNA clone encoding human lactosylceramide synthase. The deduced amino acid sequence of the human lactosylceramide synthase showed 94.2% identity with rat lactosylceramide synthase. Northern blotting analysis revealed that lactosylceramide synthase mRNA was expressed in various tissues, with the highest level in brain and adrenal gland
Keywords
L1^4 Galactosyltransferase , Lactosylceramide
Journal title
Astroparticle Physics
Record number
568223
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