• Title of article

    Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial

  • Author/Authors

    Josef S. Smolen، نويسنده , , Andre Beaulieu، نويسنده , , Andrea Rubbert-Roth، نويسنده , , Cesar Ramos-Remus، نويسنده , , Josef Rovensky، نويسنده , , Emma Alecock، نويسنده , , Thasia Woodworth، نويسنده , , Rieke Alten، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2008
  • Pages
    11
  • From page
    987
  • To page
    997
  • Abstract
    Background Interleukin 6 is involved in the pathogenesis of rheumatoid arthritis via its broad effects on immune and inflammatory responses. Our aim was to assess the therapeutic effects of blocking interleukin 6 by inhibition of the interleukin-6 recepto
  • Journal title
    The Lancet
  • Serial Year
    2008
  • Journal title
    The Lancet
  • Record number

    592657