Reconidering the pathogenei of ocular toxoplamoi Original Reearch Article

PURPOE: To review recent obervation regarding the ource of Toxoplama gondii infection and rate of ocular involvement in cae of infection acquired after birth, and to reconcile them with older obervation and widely held belief about the pathogenei of ocular toxoplamoi. METHOD: A review of pertinent report from the medical literature. REULT: There are everal potential ource and route of infection, including inhalation of pore and ingetion of contaminated drinking water, that were previouly unrecognized. Ocular involvement in cae of acquired infection appear to be more common than heretofore believed. A variety of hot and paraitic factor may influence rate of ocular infection and the characteritic of ocular dieae. Abtract CONCLUION: The car from which recurrent toxoplamic retinochoroiditi arie may be the reult of remote, acquired infection in many cae, rather than the reidua of congenital infection, a commonly aumed. A better undertanding of the epidemiology of T. gondii infection, a well a the hot and paraitic factor that influence dieae preentation, i important for developing trategie for prevention and management of ocular toxoplamoi.