Global viual field involvement in acute unilateral optic neuriti Original Reearch Article

PURPOE: To quantify automated viual field defect een at entry in the Optic Neuriti Treatment Trial (ONTT) to determine whether particular area of the field are preferentially affected and to determine the extent of viual field involvement in patient having “localized” field defect. METHOD: Review of Humphrey 30-2 Viual Field (Allergan-Humphrey, Inc, an Leandro, CA) data from the involved and fellow eye of 440 patient who were enrolled in the ONTT. Field defect were evaluated by comparing the involved eye to the fellow eye. REULT: Patient with diffue viual field defect had a relatively equal diminution of viual threhold throughout the teted 30-2 field. Patient with localized central and cecocentral cotoma had their greatet depreion of threhold centrally; however, even thoe patient with mild defect (mean defect, <6 dB) had diminution of viual threhold throughout the entire teted 30-degree field. Patient with moderate (mean defect, 6 to 20 dB) and evere (mean defect, >20 dB) central and cecocentral defect had even greater peripheral depreion. Patient with altitudinal or quadrant defect had involvement of the “unaffected” field that alo varied with the mean defect. The overall average depreion of viual threhold for all patient averaged 36% ± 4% and wa relatively uniform throughout the teted field. Abtract CONCLUION: Optic neuriti affect the entire central 30-2 field, even in patient who appear to have localized depreion of viual threhold. Optic neuriti doe not appear to have a predilection for any particular area of the viual field.