Leber hereditary optic neuropathy, progreive viual lo, and multiple-cleroi-like ymptom

PURPOE: To report a cae of Leber hereditary optic neuropathy with multiple-cleroi-like ymptom. METHOD: Obervational cae report. A 34-year-old man wa found to have Leber hereditary optic neuropathy and a mutation at poition 11778 of the mitochondrial genome. The progreion of viion lo and onet of weakne in the right leg warranted neuroimaging. REULT: Magnetic reonance imaging documented multiple leion in the brain and pinal cord. CONCLUION: Although rarely reported, progreion of optic neuropathy over month ha been previouly documented in Leber hereditary optic neuropathy. The emergence of multiple cleroi-like ymptom and ign in our patient may be part of the pectrum of Leber hereditary optic neuropathy or a coincidental occurrence.