Management of keratoconu with Intac

Purpoe To propectively tudy the effect of the ue of Intac microthin precription inert for the management of keratoconu. Deign Propective nonrandomized clinical trial. Method Thirty-three eye of 26 keratoconu patient (17 male and 9 female) age 21 to 51 year (mean age, 32 ± 9.7 year) were included in the current tudy. All patient had clear central cornea and contact len intolerance. Patient were excluded if any of the following criteria applied after the preoperative examination: previou intraocular or corneal urgery; hitory of herpe keratiti; diagnoed autoimmune dieae; and ytemic connective tiue dieae. Two Intac egment of 0.45-mm thickne were inerted in the cornea of each eye, aiming at embracing the keratoconu area to try to achieve maximal flattening. Preoperative examination included uncorrected viual acuity (UCVA), bet-corrected viual acuity (BCVA), manifet refraction, keratometric data, and corneal topography. Reult Intac were uccefully implanted in all eye. In one eye Intac were removed after 3 month becaue of their improper (uperficial) placement. The follow-up ranged from 1 to 24 month (mean: 11.3 month). The mean UCVA ignificantly improved from 0.13 ± 0.14 (range, counting finger [CF]–0.5) to 0.39 ± 0.27 (range, CF-1.0) (P < .01). Of 33 eye, 2 eye lot 1 line of UCVA, and 3 eye maintained the preoperative UCVA, wherea the ret (28 eye) experienced a 1- to 10-line gain. The mean BCVA alo improved from 0.47 ± 0.31 (range, CF-1.0) to 0.64 ± 0.26 (range, 0.1-1.0) (P < .01). Of 33 eye, 4 eye experienced 1- to 2-line lo of BCVA, 4 eye maintained the preoperative BCVA, wherea the ret (25 eye), experienced a 1- to 6-line gain. Of 3 patient (3 eye) with unatifactory reult, 1 patient improved with one egment removal and in 2 patient the egment were permanently removed. One of thee eye underwent ucceful PKP. Concluion With mean follow-up of 11.3 month, intracorneal ring egment implantation improved UCVA and BCVA in the majority of the keratoconu patient. Even though the reult are encouraging, concern till exit regarding the predictability a well a the long-term effect of uch an approach for the management of keratoconu.