A paradoxical ocular effect of brimonidine

Purpoe We report an unuual paradoxical effect of brimonidine. Deign Obervational cae report. Method A 70-year-old woman with bilateral normal tenion glaucoma wa treated with topical brimonidine and followed in an outpatient etting. The main outcome meaured wa intraocular preure (IOP) in mm Hg. Reult Brimonidine wa oberved to caue IOP elevation, confirmed on rechallenge, coring 8 (trong probability) on an advere drug reaction probability core. Concluion Under certain circumtance topical brimonidine can caue paradoxical raied IOP neceitating vigilance in follow-up of patient on topical brimonidine.