Mit Delivery of Eye Medication to the Anterior egment

Purpoe To compare the mydriatic efficacie of mit and drop delivery of tropicamide 1.0%. Deign Randomized, maked, active, controlled clinical trial. Method One hundred ubject were randomized to receive mall-volume (6 μl) mit adminitration of tropicamide 1.0% in one eye and either nothing or a conventional drop (30 μl) of the ame olution in the fellow eye. Reult Comparing mited eye with untreated eye in the ame ubject, the mean maximal increae in pupil diameter in the mited eye wa 2.02 mm and wa 0.25 mm in the fellow eye. The difference i tatitically ignificant (P ≤ .001) Comparing mit-treated eye with drop-treated eye in the ame ubject, the mean maximal increae in pupil diameter in the mited eye wa 1.98 mm and wa 2.11 mm in the drop-treated eye. The difference wa not tatitically ignificant (P = .051). Concluion mall-volume mit and conventional drop delivery of tropicamide 1.0% were hown to be imilar in mydriatic effectivene.