Relationhip of Axial Length and Retinal Vacular Caliber in Children Original Reearch Article

Purpoe Previou tudie in older adult ugget that longer axial length i aociated with narrower arteriolar caliber. In thi tudy, we re-examined thi relationhip in a cohort of children, while controlling for the effect of ocular magnification. Deign Cro-ectional tudy of 767 children aged 7 to 9 year. Method Retinal vacular caliber were meaured from retinal photograph uing a computer-baed program. Ocular magnification wa corrected uing the Bengton formula. tandardized examination of refraction and ultraound ocular biometry wa performed for all children. Reult In model that adjuted for age, gender, ethnicity, body ma index, blood preure, and birth weight, longer axial length wa aociated trongly with narrower retinal arteriolar caliber (3.18-μm decreae per tandard deviation increae in axial length; P < .001) and venular caliber (4.62-μm decreae tandard deviation increae in axial length; P < .001) before correction for ocular magnification. However, after correction, thee aociation no longer were ignificant (0.44 μm; P = .31, change for arteriolar caliber; and 0.70 μm; P = .25, for venular caliber). Concluion Our tudy in children found no aociation between axial length and retinal vacular caliber after correcting for ocular magnification, uggeting that the previouly reported aociation wa likely related to difference in ocular magnification.