Hemorrhagic Complication from Glaucoma urgery in Patient on Anticoagulation Therapy or Antiplatelet Therapy Original Reearch Article

Purpoe To determine the incidence of and rik factor for hemorrhagic complication in patient on anticoagulation (ACT) or antiplatelet therapy (APT) having glaucoma urgery. Deign Retropective cae-control tudy. Method Medical record of patient who had glaucoma urgery between July 1, 1998 and March 31, 2005 were reviewed. Patient who either ued ACT/APT continuouly throughout the perioperative period or dicontinued it ue prior to urgery were compared to cae-matched control patient who were not on uch therapie. Patient on ACT/APT who experienced potoperative hemorrhagic complication were compared to thoe who did not. Outcome meaure included hemorrhagic complication and thromboembolic event. Reult Three hundred and forty-even patient (eye) who were on ACT or APT prior to glaucoma urgery had a higher rate of hemorrhagic complication than 347 control patient (10.1% v 3.7%, repectively, P = .002). Patient on ACT had a higher rate of hemorrhagic complication than patient on APT (22.9% v 8.0%, repectively, P = .003). Patient who continued ACT during glaucoma urgery had the highet rate of hemorrhagic complication (31.8%) when compared to patient who dicontinued ACT prior to urgery or patient who ued APT alone (P = .001). Hemorrhagic complication following glaucoma urgery were more frequently aociated with preoperative ACT, arrhythmia, and higher preoperative and potoperative intraocular preure (IOP). Concluion Chronic ACT/APT wa aociated with a tatitically ignificant increae in the rate of hemorrhagic complication, and perioperative ACT and a high preoperative IOP are potential rik factor for hemorrhagic complication in patient undergoing glaucoma urgery.