Effect of exercise training on central aortic pressure wave reflection in coronary artery disease

Abstract Background Arterial stiffness is an important factor for cardiovascular performance and a predictor of cardiovascular risk. We investigated the effect of exercise training on arterial stiffness in coronary artery disease (CAD). Methods Arterial stiffness was assessed before and after 12 weeks of either exercise training or standard care in CAD patients. Arterial stiffness was evaluated by aortic augmentation index and time delay of the reflected wave (Δt) using the SphygmoCor system. Results The augmentation index decreased (30% v 26%, P< .05) and Δt increased (136 msec v 144 msec, P< .05) in patients with CAD after 12 weeks of exercise. Conclusion These results suggest that endurance exercise training improves systemic arterial stiffness in individuals with CAD.