Anti-Hepatitis B Virus Activity of Flavonoids from Marchantia Convoluta

Flavonoids from Marchantia convoluta (MCF) were studied for their ability to inhibit the proliferation of 2.2.15 cells. All concentration of MCF inhibited the secretion of HBsAg and HBeAg in the cultured me-dium by 2.2.15 cells. Analysis of morphological changes of MCF-treated cells by phase-contrast micros-copy revealed a possible mode of action for MCF: inhibition of proliferation of 2.2.15 cells by inducing apoptosis.