Osteosarcoma of the Larynx

Malignant mesenchymal tumors of the larynx constitute 0.3% to 1% of all laryngeal cancers. Of them, osteosarcoma is the rarest. Osteosarcoma of the larynx may be a difficult clinical diagnosis. Pathologic confirmation of osteoid is required for the diagnosis. Treatment is primarily surgical. It is believed that aggressive surgical intervention directed at complete tumor extirpation is the treatment of choice. Outcomes of such patients are generally poor. Most patients die because of pulmonary metastasis. A case is reported here and a review of all available published cases of osteosarcoma of the larynx is presented.