Title of article
Synthesis and Kinetic Resolution of Furyl Substituted Secondary Carbinols by Porcine Pancreatic Lipase under Solvent Free Conditions
Author/Authors
M. Mamaghani، نويسنده , , N.O. Mahmoodi، نويسنده , , A.A. Moghisseh and L. Pourmohamad، نويسنده ,
Issue Information
فصلنامه با شماره پیاپی سال 2008
Pages
6
From page
238
To page
243
Abstract
Chiral furyl substituted carbinols were prepared from the related carbonyl compounds and their enzymatic kinetic resolution was studied by using porcine pancreatic lipase (PPL) in transesterification reaction under solvent free condition. This study revealed that carbinols having one less bulky group on the chiral center are good substrates for PPL and the resolution proceeds with higher ee,s and less reaction time
Keywords
Synthesis , kinetic resolution , Porcine pancreatic lipase , Chiral furyl carbinols , Solvent free
Journal title
Journal of the Iranian Chemical Society (JICS)
Serial Year
2008
Journal title
Journal of the Iranian Chemical Society (JICS)
Record number
666610
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