Nucleophilic Substitution Reactions Using Polyacrylamide-Based Phase Transfer Catalyst in Organic and Aqueous Media

Poly [N-(2-aminoethyl) acrylamido] trimemethyl ammonium chloride was prepared and used as an effective heterogeneous phase-transfer catalyst. This modified polyacrylamide catalyzed nucleophilic displacement of alkyl halides for easy preparation of alkyl thiocyanates, alkyl cyanides, alkyl azides, and alkyl aryl ethers in high yields and short reaction times in organic and aqueous media under two-phase and triphase conditions. The catalyst can be recovered and reused several times