EFFICACY OF A 12.5% PYRIPROLE SPOT-ON SOLUTION AGAINST NATURAL FLEA (CTENOCEPHALIDES FELIS) INFESTATIONS ON DOGS

The efficacy of a 12.5% pyriprole spot-on solution against natural flea infestations applied monthly to dogs on three occasions within 60 days was investigated in patients presented at veterinary clinics in Western Australia. Twelve dogs of various breeds, age, weight, and sex were considered in the study. Six were treated with a pyriprole spot- on solution and six treated with a fipronil/ (S)-methoprene spot-on solution as positive controls. The number of fleas on each dog was counted 14 (+2) and 30 (+2) days after the first treatment, and 30 (+2) days after the second and third treatments. The geomet¬ric mean efficacy of the pyriprole spot-on solution ranged between 100% and 93.8%, and for the fipronil/(S)-methoprene solution between 98.8% and 44.7%. The treatments were well tolerated by the animals.