• Title of article

    Preferential Solvation of Ibuprofen and Naproxen in Aqueous 1,2-Propanediol

  • Author/Authors

    Yizhak Marcus، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2009
  • Pages
    5
  • From page
    40
  • To page
    44
  • Abstract
    The recently published study of the solubility of ibuprofen (IBP) and naproxen (NAP) in aqueous 1,2-propanediol (PG) at several temperatures had as its purpose the modeling of the solubilities in terms of the solvent composition. It did not show how these drugs are preferentially solvated by water and by PG. The inverse Kirkwood-Buff integral (IKBI) and the quasi-lattice quasi-chemical (QLQC) approaches are here applied to this problem of the preferential solvation. The interactions involved are deduced from the results.
  • Keywords
    2-Propanediol , inverse Kirkwood Buff integrals , 1 , naproxen , IBUPROFEN , Preferential solvation , quasi-lattice quasi chemical method
  • Journal title
    Acta Chimica Slovenica
  • Serial Year
    2009
  • Journal title
    Acta Chimica Slovenica
  • Record number

    672062