Synthesis and Biological Activity of New Series of N-[3-(1H-1,2,3-Benzotriazol-1-yl)propyl]-2-(substituted Phenyl)-3-Chloro-4-Oxo-1-Azetidinecarboxamide

The synthesis of a new series of N-[3-(1H-1,2,3-benzotriazol-1-yl)propyl]-2-(4-substituted phenyl)-3-chloro-4-oxo-1- azetidinecarboxamides 4a–s has been executed from 1,2,3-benzotriazole as a starting material by conventional method. Compounds 4a–s were screened for their antibacterial, antifungal and antitubercular activities. Structures of all the synthesized compounds were confirmed by chemical and spectroscopic analyses such as IR, 1H NMR, 13C NMR and FAB mass spectroscopy.