Title of article
Safety and Efficacy of Clomiphene Citrate and L-Carnitine in Idiopathic Male Infertility
Author/Authors
Moradi، Mahmoudreza نويسنده , , Moradi، Asaad نويسنده Fertility-Infertility Research Center, Urology and Nephrology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermansh , , Alemi، Mohsen نويسنده Fertility-Infertility Research Center, Urology and Nephrology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermansh , , Ahmadnia، Hassan نويسنده , , Abdi Oskooei، S. Hossein نويسنده , , Ahmadi، Alireza نويسنده , , Bazargan-Hejazi، Shahrzad نويسنده Department of Psychology, College of Medicine, Charles Drew University of Medicine and Science, David Geffen School of Medicine, UCLA, Los Angeles, CA ,
Issue Information
دوماهنامه با شماره پیاپی 27 سال 2010
Pages
6
From page
188
To page
193
Abstract
Purpose: To compare the effects of L-carnitine with clomiphene citrate in idiopathic infertile men. Materials and Methods: Fifty-two men with idiopathic infertility were recruited in this randomized controlled trial. They were randomly assigned into 2 treatment groups, group 1 (n = 20) and group 2 (n = 32), who received L-carnitine 25 mg/day and clomiphene citrate 2 gr/day, respectively, for a period of 3 months. Results: Comparing the effect of L-carnitine and clomiphene on sperm parameters before and after the treatment, both medications had influence on sperm count and motility (P = .01). L-carnitine significantly increased the semen volume (P = .001), while clomiphene citrate was significantly associated with the motility percentage and normal morphology (P = .008). Conclusion: It seems that the use of clomiphene citrate and L-carnitine, either individually or in combination, as the first step of idiopathic male infertility treatment is reasonable, safe, and effective.
Journal title
Urology Journal
Serial Year
2010
Journal title
Urology Journal
Record number
676571
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