• Title of article

    Enhanced relaxation of nanoparticle-bound supercoiled DNA in X-ray radiation

  • Author/Authors

    Guo، Jang-Ting نويسنده , , Foley، Erika A. نويسنده , , Carter، Joshua D. نويسنده , , Shan، Fang نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    -3191
  • From page
    3192
  • To page
    0
  • Abstract
    A therapeutic methodology was developed based on the large X-ray absorption cross-section of gold nanoparticles at high photon energies (>81 keV). Experimental results showed that the amounts of the relaxed circular supercoiled DNA (scDNA) for gold nanoparticle-bound scDNA were more than doubled compared to that for free scDNA under otherwise identical radiation conditions.
  • Journal title
    CHEMICAL COMMUNICATIONS - LETCHWORTH
  • Serial Year
    2005
  • Journal title
    CHEMICAL COMMUNICATIONS - LETCHWORTH
  • Record number

    68144